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Liver Function Tests (LFT) During Pregnancy

Pregnancy is a time of profound physiological change, and the liver plays a crucial role in adapting to these demands. Liver Function Tests (LFTs) are blood tests that measure enzymes, proteins, and substances produced or processed by the liver. They help clinicians assess whether the liver is functioning normally and detect complications early.


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Why LFTs Matter in Pregnancy

  • Physiological changes: Pregnancy naturally alters liver enzyme levels, so reference ranges differ from non-pregnant women.

  • Early detection: Abnormal results may indicate pregnancy-specific liver conditions such as intrahepatic cholestasis of pregnancy (ICP), HELLP syndrome, or acute fatty liver of pregnancy.

  • Maternal & fetal safety: Monitoring ensures timely intervention, reducing risks for both mother and baby.


Normal Reference Ranges in Pregnancy

According to clinical guidelines, trimester-specific ranges differ from non-pregnant values:


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What is SGPT

  • Full form: Serum Glutamic Pyruvic Transaminase (also called Alanine Aminotransferase – ALT)

  • Where it’s found: Primarily in the liver, with smaller amounts in kidneys and heart

  • Function: Helps break down amino acids and proteins to generate energy for cells

  • Clinical use:

  • A blood test for SGPT is one of the most common liver function tests.

  • High SGPT levels usually point to liver injury or inflammation, such as hepatitis, fatty liver, or alcohol-related damage.

What is SGOT

Full form: Serum Glutamic-Oxaloacetic Transaminase (also called Aspartate Aminotransferase – AST)

• Where it’s found: Mostly in the liver, but also in the heart, muscles, kidneys, and brain

• Function: Plays a role in amino acid metabolism and energy production

• Clinical use:

• SGOT levels rise when liver cells or other tissues are damaged.

• Doctors often compare SGOT with SGPT to determine whether the damage is liver-specific or related to other organs.


Safe Home Foods for Pregnancy & Liver Health

Foods to Include

  • Fresh fruits: Papaya (ripe), apple, orange, pomegranate, watermelon – rich in antioxidants and vitamins.

  • Green leafy vegetables: Spinach, fenugreek, kale – provide iron and folate, supporting liver detox.

  • Fresh Sugarcane juice helps in regulating SGOT & SGPT

  • Whole grains: Brown rice, oats, whole wheat chapati – easy to digest and improve metabolism.

  • Legumes & pulses: Moong dal, masoor dal – light proteins that don’t burden the liver.

  • Lean proteins: Boiled eggs, grilled chicken, fish (low-mercury options like salmon) – help repair tissues.

  • Healthy fats: Flax seeds, walnuts, almonds – provide omega-3s for liver protection.

  • Hydration: Coconut water, buttermilk, lemon water – natural detoxifiers that keep bile flow smooth.


Foods to Avoid

  • Fried snacks, pakoras, samosas – high in trans fats.

  • Sugary foods – sweets, soft drinks, packaged juices.

  • Spicy and oily curries – irritate the liver and digestive system.

  • Red meat – harder to digest and increases liver strain.

  • Excess salt – worsens water retention and blood pressure.


Lifestyle Tips Alongside Diet

  • Eat small, frequent meals to reduce liver load.

  • Practice gentle exercise like walking or prenatal yoga.

  • Ensure adequate sleep to support liver regeneration.

  • Avoid self-medication; always consult your doctor before supplements.


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